Masu bincike a Cibiyar Kiwon Lafiya ta Jami'ar Columbia (CUMC) a Amurka sun yi nasarar kutsawa cikin tsarin garkuwar jikin kwayoyin halittar kwayar halittar hanjin mutum 'Escherichia coli' zuwa kwatankwacin rakoda mai rikodin kwayoyin halitta wanda za a iya amfani da shi don bin alamun da lokaci. Tare da ƙarin ƙoƙari, masana kimiyya suna buɗe hanya don sabbin fasahohin da zasu iya amfani da ƙwayoyin ƙwayoyin cuta daga ganewar cutar zuwa kula da muhalli a nan gaba.
Kwayoyin da aka yiwa kutse zasu iya amsawa ga canjin sunadarai a cikin kewayen sannan kuma 'sanya musu lokaci' a cikin DNA. "Irin wadannan kwayoyin cuta, wadanda mara lafiya suka hadiye, na iya yin rikodin sauye-sauyen da suka samu ta hanyar dukkanin hanyoyin narkar da abinci, suna samar da wani ra'ayi na ba-sani-ba-gani game da abubuwan da ba za a iya riskar su ba a baya," in ji Harris Wang, babban marubucin littafin Kimiyya.
Masana kimiyya sun hada gwiwa da tsarin gyaran kwayar halitta da ake kira CRISPR-Cas a cikin kwayar cutar Escherichia coli, don yin rikodin bayanan watau bayanan kwayoyin cutar cikin kwayoyin cuta. CRISPR-Cas wani inbuilt ne rigakafi da tsarin a cikin wasu bacteriaan kwayoyin da ke adana ƙwayoyin halittar DNA daga ƙwayoyin cuta waɗanda suka afka wa kwayar don ganowa da samar da juriya ga ƙarin kai hare-hare ta irin ƙwayoyin cuta.
“Tsarin CRISPR-Cas na’urar ƙwaƙwalwa ce ta halitta. Daga hangen nesa abin da yake da kyau kwarai da gaske saboda tuni ya kasance tsarin da aka tsara shi ta hanyar juyin halitta ya zama da gaske wajen adana bayanai, ”in ji Harris Wang.
Ravi Sheth, dalibin da ya kammala karatun digiri a dakin bincike na Wang kuma marubucin marubucin jaridar ya ce, “Lokacin da kake tunanin yin rikodin sigina na zamani da na lantarki, ko na’urar daukar sauti audio wannan fasaha ce mai matukar karfi, amma muna tunanin ta yaya za ka iya fadada wannan ga kwayoyin rai da kansu? "
Hakan ne lokacin da masana kimiyya suka sake fasalin madaidaicin DNA da ake kira plasmids a cikin ƙwayoyin cuta don adana lokaci da abubuwa masu ɓarna a laburaren bayanan su. Bayan adana bayanan, don juya shi zuwa na'urar rikodi watau adana waɗannan ayyukan a cikin tsari ƙungiyar ta yi amfani da kayan aikin CRISPR-Cas spacer don ɗora su a cikin jeri don fassara shi azaman ma'aunin lokaci.
CRISPR an taɓa amfani da shi ta logistswararrun logistswararrun logistswararrun ntwararru don adana baitoci, littattafai, da hotuna a cikin DNA, amma wannan shi ne karo na farko da aka yi amfani da CRISPR don yin rikodin ayyukan salula da lokacin waɗannan abubuwan.
"Yanzu muna shirin duba alamomi daban-daban wadanda za a iya canzawa a yayin canjin yanayi ko jihohin cuta, a tsarin tsarin ciki da sauran wurare," in ji Wang